Welcome

Christopher Brett is an Assistant Professor of Biology and Canada Research Chair at Concordia University and Adjunct Professor of Anatomy & Cell Biology  at McGill University in beautiful Montréal, QC, Canada. His research program is dedicated to understanding how the endocytic system functions and how defects in this pathway lead to symptoms associated with neurodevelopmental disorders like autism, mental retardation and ADHD.


The ion and membrane transport laboratory

Specializing in both yeast and neural cell biology, our lab is dedicated to understanding how sodium hydrogen exchangers (ion transporters) and the fusion machinery (responsible for membrane transport or trafficking) work together in the endocytic system to control protein degradation, to determine organelle size, shape and number, and to allow synaptic pruning in neurons. Mutations in genes responsible for endocytosis - such as NHE9, a sodium hydrogen exchanger - are linked to autism spectrum disorders and ADHD. By determining the effects of these mutations on endocytic function, we aim to uncover the cellular basis of these diseases - a necessary step towards developing treatments.  Our lab is affiliated with the Groupe d'Étude des Protéines Membranaires (GÉPROM), the Centre de recherche sur la conception, les mechanismes d'action et la vectorisation des médicaments (Pharmaqam) and the Centre for Microscopy at Concordia (CMAC). Check out the research page for more details, and have a look at the publications page for a complete list of research articles from the lab.


Research opportunities updated Nov 2014

NEW GRADUATE STUDENT POSITIONS ARE AVAILABLE IN 2015!!!

Applicants must have experience studying endocytosis, membrane fusion, or ion transport in yeast. Check out the opportunities page for details.


Laboratory news updated Sep 2014

Sep 23 2014 The Centre for Microscopy At Concordia is recognized by the University as a Research Unit. This commitment to microscopy-based research on campus includes financial support needed to operate the centre.

Sep 04 2014 A warm welcome to Domenic Arcuri a new B.Sc. honours student in the lab.

Apr 26 2014 Congratulations! and a warm welcome to Matthew Carnevale a NSERC USRA recipient and new B.Sc. honours student in the lab.

Apr 19 2013 Congratulations! and a warm welcome to new graduate student Jeremy Glass-Pilon a Concordia USRA and NSERC Master's Fellowship recipient. Jeremy is also a leader of Concordia's iGEM team. Keep up the great work Jeremy!


Want to meet the group?

Check out the members page, or If you want to meet us in person, check out the meetings page for a list of local meetings and scientific conferences that we will be attending in the near future.


Questions?

Please feel free to contact us.


Funding generously provided by


find us @

Concordia University
Loyola Campus
Biology Department
7141 Sherbrooke St W
SP-534.00
Montréal, QC Canada
H4B 1R6
514 848 2424 
x5988 lab
x3398 office


concordia

concordia universitycmac • biologymyConcordiasimsshuttle • cscis

affiliations

crcgépromcsfg • cmac • pharmaqamcasbmcgill cell bio

montréal

environment canadastmmpl

funding

cihr • nserc • crc • cfi  • frq

science

pubmedsgdbiogridpdbtcdballen brain map • google scholar

friends

michael sacher, concordia • john oh, concordia • jean-louis schwartz, u de m • harley kurata, ubc • sarah jenna, uqam • hojatollah vali, mcgill • • alisa piekny, concordia • alex merz, uw • stéphane lefrançois, u de m • david walsh, concordia • gord rintoul, sfu • frank lynn, ubc • jahn ehses, ubc • vlad titorenko, concorida • guillaume lamoureux, concordia • rajini rao, johns hopkins • mark donowitz, johns hopkins • gyanu lamichanne, johns hopkins • olga kovbasnjuk, johns hopkins • steve walkley, albert einstein 

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