Full Lists and MetricS 

Hurst LR, Zhang C, Kazmirchuk TDD, RiveraKohr DR, Brett CL, Fratti RA. (2020)

Sphingolipids with Very Long-Chain Fatty Acids Regulate Vacuole Fusion During Tethering and Docking

BioRxiv 953331


Patel D, Brett CL. (2018)

Acetate And Hypertonic Stress Stimulate Organelle Membrane Fission Using Distinct Phosphatidylinositol Signals

BioRxiv 398685

McNally EK, Brett CL. (2017)

ILF And VRED Pathways Cooperate To Control Lysosomal Transporter Protein Lifetimes

BioRxiv 204396



Mattie S, Kazmirchuk T, Mui J, Vali H, Brett CL. (2019)

Visualization of SNARE-Mediated Organelle Membrane Hemifusion by Electron Microscopy Methods in Molecular Biology. 1860:361-377.

Karim MA, Samyn DR, Brett CL. (2019)

A Cell-Free Content Mixing Assay for SNARE-Mediated Multivesicular Body-Vacuole Membrane Fusion

Methods in Molecular Biology. 1860:289-301.



McNally EK, Brett CL. (2018)

The Intralumenal Fragment Pathway Mediates ESCRT-Independent Surface Transporter Down-Regulation

Nature Communications. 9(1):5358.

Karim MA, McNally EK, Samyn DR, Mattie S, Brett CL. (2018)

Rab-Effector-Kinase Interplay Regulates Intralumenal Fragment Formation During Vacuole Fusion

Developmental Cell. 47:80-97.

Karim MA, Samyn DR, Mattie S, Brett CL. (2018)

Distinct Features of Multivesicular Body-Lysosome Fusion Revealed By A New Cell-Free Content-Mixing Assay

Traffic. 19:138-149.

Karim MA, Brett CL. (2018)

The Na+(K+)/H+ Exchanger Nhx1 Controls Multivesicular Body-Vacuolar Lysosome Fusion 

Molecular Biology of the Cell. 29:317-325. *Highlighted in ASCB Newsletter.


McNally EK, Karim MA, Brett CL. (2017)

Selective Lysosomal Transporter Degradation By Organelle Membrane Fusion

Developmental Cell. 40:151-167. *Recommended by F1000.

Mattie S, McNally EK, Karim MA, Vali H, Brett CL. (2017)

How And Why Intralumenal Membrane Fragments Form During Vacuolar Lysosome Fusion 

Molecular Biology of the Cell. 28:309-321. *Highlighted in ASCB Newsletter.


Börgershusen N, et al. (2013)

Recessive TRAPP Mutations Cause A Disease Spectrum Of Limb Girdle Muscular Dystrophy And Myopathy With Movement Disorder And Intellectual Disability

American Journal of Human Genetics. 93:181-190.

Khorsand B, Lapointe G, Brett CL, Oh JK. (2013)

Intracellular Drug Delivery  Nanocarriers of Glutathione-Responsive Degradable Block Copolymers Having Pendant Disulfide Linkages

Biomacromolecules 14:2103-2111.



Lockshon D, Olsen CP, Brett CL, Chertov A, Merz AJ, Lorenz DA, Van Gilst MR, Kennedy BK. (2012)

Rho Signaling Participates in Membrane Fluidity Homeostasis

PLoS One. 7:e45049.

Lo SY, Brett CL, Plemel RL, Vignali M, Fields S, Gonen T, Merz AJ (2012)

Intrinsic Tethering Activity Of Endosomal Rab Proteins

Nature Structural and Molecular Biology. 19:40-47. *Recommended by F1000.


Kallay LM, Brett CL, Tukaye DN, Wemmer MA, Chyou A, Odorizzi G, Rao R. (2011)

Endosomal Na+(K+)/H+ Exchanger Nhx1/Vps44 Functions Independently and Downstream of Multivesicular Body Formation

Journal of Biological Chemistry. 286:44067-44077.

Brett CL, Kallay, Hua Z, Green R, Chou A, Zhang Y, Graham TR, Donowitz M, Rao R. (2011)

Genome-Wide Analysis Reveals The Vacuole pH-stat of Saccharomyces cerevisiae

PLoS One. 6:e17619.

Plemel RL, Lobingier BT, Brett CL, Angers CG, Nickerson DP, Pausel A, Sprague D, Merz AJ (2011)

Subunit Organization and Rab Interactions of Vps-C Protein Complexes That Control Endolysosomal Membrane Traffic

Molecular Biology of the Cell. 22:1353-1363.


Nickerson DP, Brett  CL, Merz AJ. (2009)

Vps-C Complexes: Gatekeepers of Endolysosomal Traffic

Current Opinion in Cell Biology. 21:543-551.


Brett CL, Plemel RL, Lobingier BT, Vignali M, Fields S, Merz AJ. (2008)

Efficient Termination of Vacuolar Rab GTPase Signalinng Requires Coordinated Action by a GAP and a Protein Kinase

Journal of Cell Biology. 182:1141-1151. *Recommended by F1000. **JCB highlighted paper.

Brett CL, Merz AJ. (2008)

Osmotic Regulation of Rab-Mediated Organelle Docking

Current Biology. 18:1072-1077.


Hill JK, Brett CL, Chyou A, Kallay, Sakaguchi M, Rao R, Gillespie PG. (2006)

Vestibular Hair Bundles Control pH with Na+(K+)/H+ Exchangers NHE6 and NHE9

Journal of Neuroscience. 26:9944-9955.

Mukherjee S, Kallat L, Brett CL, Rao R. (2006)

Mutational Analysis of the Intramembranous H10 Loop of Yeast Nhx1 Reveals a Critical Role in Ion Homeostasis and Vesicle Trafficking

Biochemical Journal. 398:97-105.

Brett CL, Donowitz M, Rao R. (2006)

Does the Proteome Encode Organellar pH?

FEBS Letters. 580:717-719.


Donowitz M, Cha B, Zachos NC, Brett CL, Sharma A, Tse CM, Li X. (2005)

NHERF Family and NHE3 Regulation

Journal of Physiology. 567:3-11.

Brett CL, Donowitz M, Rao R. (2005)

Evolutionary Origins of Eukaryotic Sodium/Proton Exchangers

American Journal of Physiology. 288:C223-C239.

Brett CL, Tukaye DN, Mukherjee S, Rao R. (2005)

The Yeast Endosomal Na+(K+)/H+ Exchanger Nhx1 Regulates pH to Control Vesicle Trafficking

Molecular Biology of the Cell. 16:1396-1405. *Recommended by F1000.


Ali R, Brett CL, Mukherjee S, Rao R. (2004)

Inhibition of Sodium/Proton Exchange by  a Rab-GTPase-Activating Protein Regulates Endosomal Traffic in Yeast

Journal of Biological Chemistry. 279:4498-4506.


Brett CL, Kelly T, Sheldon C, Church J. (2002)

Regulation of Cl-/HCO3- Exchangers by cAMP-Dependent Protein Kinase in Adult Rat Hippocampal CA1 Neurons

Journal of Physiology. 545:837-853.

Brett CL, Wei Y, Donowitz M, Rao R. (2002)

Human Na+/H+ Exchange Isoform 6 Is Found in Recycling Endosomes of Cells, Not Mitochondria

American Journal of Physiology. 282:C1031-1041.


Diarra A, Sheldon C, Brett CL, Baimbridge KG, Church J. (1999)

Anoxia-Evoked Intracellular pH and Ca2+ Concentration Changes in Cultured Postnatal Rat Hippocampal Neurons

Neuroscience. 93:1003-1016.


Smith GA, Brett CL, Church J. (1998)

Effects of Noradrenaline on Intracellular pH in Acutely Dissociated Adult Rat Hippocampal CA1 Neurones

Journal of Physiology. 512:487-505.

© 2020 by Christopher L. Brett